Original Investigation

Blood Pressure Trajectory From Birth to Preschool and School Age in the ENVIRAGE Birth Cohort

JAMA Network Open 10.1001/jamanetworkopen.2025.51361

January 13, 2026 at 11:00 AM EST

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Is blood pressure (BP) at birth and in early childhood associated with BP in later childhood?In this cohort study of 500 children with BP measured at birth, preschool age (4-6 years), and school age (9-11 years), BP tracked over time. The risk of elevated BP and hypertension at preschool age and school age was associated with BP levels at birth and early childhood.These findings suggest the importance of monitoring and managing BP from birth as a potential strategy to reduce cardiovascular risk later in childhood.

Corresponding Author: Tim S. Nawrot, PhD, Centre for Environmental Sciences, Hasselt University, Agoralaan gebouw D, 3590 Diepenbeek, Belgium (tim.nawrot@uhasselt.be).

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