Racial and Ethnic Disparities in Persistent Chemotherapy-Induced Alopecia Among Women With Breast Cancer

Do racial and ethnic differences exist in the incidence of persistent chemotherapy-induced alopecia (PCIA) among women with breast cancer?In this cohort study of 304 patients with stage I to III breast cancer, PCIA incidence at 12 months after chemotherapy was highest among Asian women (42%), followed by non-Hispanic White (22%), Black (10%), and Hispanic or Latino (5%) women. Racial and ethnic differences based on hair structure, genetic variants, and sociocultural context were observed.The findings of this study support the need for personalized risk communication and culturally sensitive supportive care to address long-term toxicities of chemotherapy.

Corresponding Author: Juhee Cho, PhD, Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, 115 Irwon-ro, Gangnam, Seoul 06335, South Korea (jcho@skku.edu); Mario E. Lacouture, MD, Department of Dermatology, NYU Langone Ambulatory Care Garden City, 1111 Franklin Ave, Suite 1262, Garden City, NY (mario.lacouture@nyulangone.org).

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