Development of a Health-Related Quality of Life Tool for Adolescents and Young Adults With Cancer
JAMA Network Open 10.1001/jamanetworkopen.2025.49071December 19, 2025 at 11:00 AM EST
Can a cross-cultural questionnaire be developed to comprehensively assess health-related quality of life (HRQOL) in adolescents and young adults (AYAs) with cancer?In this survey study involving 253 AYAs from 19 countries, a 30-item HRQOL questionnaire was developed that assesses HRQOL issues of importance and relevance to AYAs from diverse cultures with different cancer and treatment types.Findings of this study suggest that the HRQOL questionnaire provides a reliable, valid tool for use in both clinical trials and practice.
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