Original Investigation

Climate Vulnerability Index and Incident Type 2 Diabetes in a Large Integrated Health Care System

JAMA Network Open 10.1001/jamanetworkopen.2025.47119

December 05, 2025 at 11:00 AM EST

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Is residence in communities with a higher Climate Vulnerability Index (CVI) associated with an increased risk of incident type 2 diabetes?In this retrospective cohort study of more than 1 million adults without baseline diabetes, residence in the highest vs lowest CVI quartile was associated with higher diabetes incidence (2.66 vs 1.48 cases per 100 person-years; 14.1% vs 8.6% at 7 years), a statistically significant difference.These findings suggest that living in higher-CVI communities is associated with greater diabetes risk; incorporating place-based vulnerability into clinical risk stratification and public health planning may help target prevention.

Corresponding Author: Sadeer Al-Kindi, MD, Center for Cardiovascular Computational and Precision Health (C3PH), Department of Cardiology, Houston Methodist DeBakey Heart sal-kindi@houstonmethodist.org).

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