Condition-Specific Growth Charts for Children With Alagille Syndrome

What do condition-specific growth charts look like for children with Alagille syndrome (ALGS)?In this case series of 1204 children with ALGS, growth charts developed for boys and girls using modern statistical techniques based on 9855 weight and 8463 height observations showed markedly different growth patterns when overlaid with US growth charts for children with typical development.These findings suggest that condition-specific growth charts may provide references for the growth of children with ALGS and how the condition responds to new therapies.

Corresponding Author: Koen Huysentruyt, MD, PhD, Division of Pediatric Gastroenterology, Hepatology and Nutrition, UZ Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium (koen.huysentruyt@uzbrussel.be).

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