Cognitive Outcomes of Children Exposed to Selective Serotonin Reuptake Inhibitors Through Breast Milk
JAMA Network Open 10.1001/jamanetworkopen.2025.44989November 21, 2025 at 11:00 AM EST
Is maternal treatment with selective serotonin reuptake inhibitors (SSRIs) during breastfeeding associated with cognitive performance of the offspring?This cohort study of 97 children who were exposed to maternal treatment with SSRIs during pregnancy with or without exposure during breastfeeding underwent testing with the Wechsler Scales of Preschool and Primary Intelligence. Fully adjusted mean full-scale, verbal, and performance IQ scores were similar among breastfed children exposed to SSRIs, breastfed children not exposed to SSRIs, and nonbreastfed children.These findings suggest that maternal treatment with SSRIs during breastfeeding does not affect the cognitive performance of the offspring.
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