Low-Molecular-Weight Heparin Plus Insulin in Hypertriglyceridemic Acute Pancreatitis

Is low-molecular-weight heparin combined with insulin superior to insulin alone in improving clinical outcomes in hypertriglyceridemic pancreatitis?In this multicenter randomized clinical trial of 533 adults with acute pancreatitis, low-molecular-weight heparin with insulin was not superior to insulin alone in reducing new-onset organ failure and/or mortality.Low-molecular-weight heparin might not be necessary for early lipid-lowering in hypertriglyceridemic acute pancreatitis.

Corresponding Authors: Yin Zhu, MD, Department of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 17 Yongwaizheng St, Nanchang, Jiangxi, China 330006 (ndyfy01977@ncu.edu.cn); Nonghua Lv, MM, Department of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, No. 17 Yongwaizheng St, Jiangxi, China 330006 (lunonghua@ncu.edu.cn).

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