Original Investigation

Validation of 4 Risk Stratification Tools for Delirium in the Emergency Department

JAMA Network Open 10.1001/jamanetworkopen.2025.40920

November 03, 2025 at 11:00 AM EST

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Are previously developed delirium risk stratification tools applicable to a different setting in the emergency department (ED)?In this prognostic study including 44 578 patients, 3 of the 4 delirium scores demonstrated performance that was comparable with the scores attained in the original studies. The Recognizing Delirium in Emergency Medicine (REDEEM) score demonstrated the strongest predictive capacity, and the Mayo Delirium Prediction (MDP) tool, despite being developed for hospitalized patients, exhibited a high degree of accuracy in detecting delirium in ED patients.These findings suggest that the REDEEM score and the MDP tool may be valid instruments to potentially improve delirium detection rates in the ED.

Corresponding Author: Fernanda Bellolio, MD, MSc, Department of Emergency Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (bellolio.fernanda@mayo.edu).

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