Maternal Psychological Distress Before and After Childbirth and Neurodevelopmental Delay in Toddlers
JAMA Network Open 10.1001/jamanetworkopen.2025.40907October 31, 2025 at 11:00 AM EDT
Is the timing of maternal psychological distress differentially associated with the risk of neurodevelopmental delay in toddlers?In this birth cohort study of 82 418 mother-child pairs, maternal psychological distress at 1 year post partum had an estimated higher risk of neurodevelopmental delay in toddlers than psychological distress during mid- to late pregnancy, with no salient multiplicative interaction between time points observed.These findings suggest the importance of maintaining maternal mental health from pregnancy through 1 year post partum.
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