Original Investigation

Web-Based Guided Self-Help vs Treatment as Usual for Binge-Eating Disorder

JAMA Network Open 10.1001/jamanetworkopen.2025.36644

October 10, 2025 at 11:00 AM EDT

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Is web-based guided self-help noninferior to treatment as usual for adults with binge-eating disorder?In this randomized clinical trial of 187 adults with binge-eating disorder, web-based guided self-help was noninferior to treatment as usual in reducing binge-eating episodes at both the end of treatment and at 20 weeks after treatment.The findings of this study suggest that web-based guided self-help is an effective standalone treatment for adults with binge-eating disorder and may be beneficial for challenges in the global mental health field.

Corresponding Author: Ella van Beers, MSc, Novarum Centre for Eating Disorders and Obesity, Laan van de Helende Meesters 2, 1186 AM Amstelveen, the Netherlands (ella.van.beers@novarum.nl).

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