Lung Cancer Screening in Cancer Survivors vs Those Without a History of Cancer

What are the differences between cancer survivors and individuals without prior cancer undergoing lung cancer screening (LCS)?In this cohort study of 814 cancer survivors and 6481 individuals without prior cancer undergoing LCS, cancer survivors were more likely to be older and have increased comorbidities. Rates of positive low-dose computed tomography scans were similar between the 2 groups, but rates of lung cancer detection and all-cause mortality were slightly higher among cancer survivors.These findings suggest that LCS may result in early detection of second primary lung cancer in cancer survivors and should be evaluated in larger studies.

Corresponding Author: M. Patricia Rivera, MD, Department of Medicine, Division of Pulmonary and Critical Care Medicine, The University of Rochester Medical Center, 601 Elmwood Ave, Box 692, Rochester, NY 14642 (patricia_rivera@urmc.rochester.edu).

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