Research Letter

Prevalence of Clinical Obesity in US Adults Based on a Newly Proposed Definition

JAMA Network Open 10.1001/jamanetworkopen.2025.33806

September 25, 2025 at 11:00 AM EDT

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This cross-sectional study compares the prevalence of obesity among US adults using 2 definitions: a body mass index–based definition and a new evidence-based definition of clinical obesity focusing on direct measures of body fat and organ dysfunction and physiological impairment.

Corresponding Authors: S. V. Subramanian, PhD, Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA 02115 (svsubram@hsph.harvard.edu); Min-Jeong Shin, PhD, School of Biosystems and Biomedical Sciences, College of Health Science, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, South Korea (mjshin@korea.ac.kr).

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