Age, Sex, BMI, Meal Timing, and Glycemic Response to Meal Glycemic Load
JAMA Network Open 10.1001/jamanetworkopen.2025.33193September 23, 2025 at 11:00 AM EDT
Are the glycemic load of mixed meals, age, sex, body mass index (BMI), and meal timing associated with postprandial glucose responses in individuals without diabetes?In this cross-sectional study of 514 adults without diabetes, meals with higher glycemic load were associated with sustained blood glucose elevation, particularly after lunch and dinner. Age notably modified curves of glucose levels after meals, whereas greater BMI was associated with higher and male sex with lower postprandial glucose levels.These findings suggest that glycemic load is associated with postprandial glucose response in the general population of adults without diabetes, accounting for meal timing, age, sex, and BMI.
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