Prevalence and Trajectories of Perinatal Anxiety and Depression in a Large Urban Medical Center
JAMA Network Open 10.1001/jamanetworkopen.2025.33111September 22, 2025 at 11:00 AM EDT
What are the rates of screening, treatment, and prevalence of clinically meaningful perinatal depression and anxiety over time in a large urban medical center?Among 27 393 perinatal women, only 3.0% to 14.2% were screened for anxiety and depression, and in clinics with mandatory screening, 23.2% of women reported clinical depression symptoms and 8.8% reported suicidality. Women who received mental health services (17.1%) showed a more rapid depression reduction and sustained gains, compared with untreated women.These findings suggest that there is a need for routine mental health screening, monitoring, and timely interventions to improve risk detection and reduce perinatal depression and anxiety.
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