Original Investigation

Survival by Treatment Recommendation and Receipt Among Older Patients With Early-Stage Cervical Cancer

JAMA Network Open 10.1001/jamanetworkopen.2025.32206

September 16, 2025 at 11:00 AM EDT

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What are the survival differences by treatment recommendation and treatment receipt among patients with early-stage cervical cancer aged 65 years or older?In this cohort study of 2236 patients with early-stage cervical cancer aged 65 years and older, receiving recommended surgery or radiotherapy was significantly associated with a lower risk of cervical cancer–specific mortality compared with refusing or not receiving recommended treatment, after adjusting for other treatment factors and the number of cancer diagnoses.In this study, older patients with localized cervical cancer who received recommended treatments experienced substantial survival benefits.

Corresponding Author: Ryan Suk, PhD, MS, Nell Hodgson Woodruff School of Nursing, Emory University, 1520 Clifton Rd, Atlanta, GA 30322 (ryan.suk@emory.edu).

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