Clinical Outcomes in Patients With Quadricuspid vs Bicuspid Aortic Valve

Do morbidity and survival outcomes differ between patients with quadricuspid aortic valve (QAV) vs bicuspid aortic valve (BAV)?In this cohort study of 139 patients with QAV and 695 with BAV matched 1:5 by age and sex, those with QAV had a similarly high incidence of aortic valve intervention, more coexisting cardiomyopathies, and an increased risk of heart failure hospitalization compared with those with BAV. Both groups had survival comparable to that of the age- and sex-matched general population.Patients with QAV may benefit from closer surveillance of valve function and systematic screening for cardiomyopathy.

Corresponding Author: Kai-Hang Yiu, MD, PhD, Division of Cardiology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Rd, Block K, Room 1928, Hong Kong 999077, Hong Kong SAR, China (khkyiu@hku.hk).

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