Original Investigation

Early Cardiac Rehabilitation for Critically Ill Patients With Acute Decompensated Heart Failure

JAMA Network Open 10.1001/jamanetworkopen.2025.24141

July 30, 2025 at 11:00 AM EDT

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Are there benefits of early cardiac rehabilitation for physical function and rehospitalization for critically ill patients with acute decompensated heart failure (ADHF) admitted to the cardiac intensive care unit?In this randomized clinical trial involving 120 critically ill patients with ADHF, there were no significant differences in Short Physical Performance Battery (SPPB) scores or rehospitalization rates between the group receiving cardiac rehabilitation and the group receiving usual care.An early, personalized cardiac rehabilitation program did not alter SPPB scores or rehospitalization rates for critically ill patients with ADHF compared with usual care.

Corresponding Authors: Cuilian Dai, MD (daicl@xmu.edu.cn), and Binbin Liu, PhD (liubinbin@xmu.edu.cn), Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Fujian Branch of National Clinical Research Center for Cardiovascular Diseases, 2999 Jinshan Rd, Xiamen 361015, China.

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