Computed Tomographic Screening Intervals for Patients at Moderate Risk of Lung Cancer

Can the benefits of lung cancer screening be preserved while reducing the burden by adapting the annual screening interval to age, sex, and smoking history?In this economic evaluation including 3 microsimulation models of lung cancer screening, starting with biennial screening for individuals aged 50 to 60 years preserved most of the benefits (96% of deaths prevented) while requiring 21% fewer computed tomographic screens.These findings suggest that the screening interval may be relaxed to biennial with little loss of benefit for those at a moderate risk of lung cancer, particularly participants aged 50 to 60 years.

Corresponding Author: Koen de Nijs, MSc, Department of Public Health, Erasmus University Medical Center Rotterdam, 3015 CE Rotterdam, the Netherlands (k.denijs@erasmusmc.nl).

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