Original Investigation

Changes in Medicare Part D Plan Designs After the Inflation Reduction Act

JAMA Internal Medicine 10.1001/jamainternmed.2025.4003

August 18, 2025 at 11:00 AM EDT

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How did prescription drug coverage in Medicare Part D plans change after the Inflation Reduction Act (IRA)?In this cross-sectional study of enrollees in Medicare Part D stand-alone and Medicare Advantage plans, from 2019 to 2025 mean deductibles and the proportion of patients with coinsurance for preferred brand-name drugs increased. For stand-alone plans, these increases were observed before and after the IRA changes took effect in 2025, but for Medicare Advantage plans, the changes were abrupt in 2025.The IRA limited annual out-of-pocket costs to $2000 for Medicare Part D beneficiaries, but concurrent design changes by Part D insurers, particularly among Medicare Advantage plans, may lead to higher cost sharing for some beneficiaries who do not reach this limit in 2025.

Corresponding Author: Christopher L. Cai, MD, Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, 1620 Tremont St, Ste 3030, Boston, MA 02120 (ccai@bwh.harvard.edu).

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