Research Letter

Isotretinoin Risk Evaluation and Mitigation Strategy and Pregnancy Incidence

JAMA Internal Medicine 10.1001/jamainternmed.2025.3168

July 21, 2025 at 11:00 AM EDT

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This cohort study examines pregnancy incidence among publicly and commercially insured female patients using isotretinoin vs topical retinoids, stratified by patient characteristics.

Corresponding Author: Yanmin Zhu, PhD, MS, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 1620 Tremont St, Ste 3030, Boston 02120 (yzhu15@bwh.harvard.edu).

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