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E-Cigarettes in Historical Context—Innovation, Risk, and Regulation

JAMA Health Forum 10.1001/jamahealthforum.2025.4629

October 17, 2025 at 11:00 AM EDT

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This Viewpoint discusses the potential for e-cigarettes to displace smoking, restrictive regulations, and public misperceptions amid enduring nicotine demand and persistent smoking-related disease.

Corresponding Author: Michael F. Pesko, PhD, Department of Economics, University of Missouri, 615 Locust St, Columbia, MO 65201 (peskom@missouri.edu).

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