Research Letter

Keratinocyte Cancer Risk and Porokeratosis Mevalonate Pathway Variants

JAMA Dermatology 10.1001/jamadermatol.2026.1765

May 15, 2026 at 11:35 AM EDT

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This cohort study evaluates the association of genetically diagnosed porokeratosis and skin cancer.

Corresponding Authors: Lihi Atzmony, MD (lihi.atzmonymaoz@yale.edu), and Keith A. Choate, MD, PhD (keith.choate@yale.edu), Department of Dermatology, Yale School of Medicine, 333 Cedar St, PO Box 208059, New Haven, CT 06520.

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