Intraocular Pressure During Short-Term Topical or Systemic Corticosteroid Treatment

Does short-term use of a topical or systemic corticosteroid increase intraocular pressure (IOP) in adults with or without atopic dermatitis?In 3 randomized clinical trials including 84 adults treated with periocular, whole-body, or systemic corticosteroids, short-term corticosteroid use did not increase IOP. A significant decrease of –2.5 mm Hg in IOP was observed in patients with periocular atopic dermatitis, with no significant increases in any group.These findings suggest that short-term use of a topical or systemic corticosteroid does not increase IOP, supporting its ocular safety for short-term treatment courses.

Corresponding Author: Lise Gether, MD, PhD, Department of Dermatology and Allergy, Herlev-Gentofte Hospital, Gentofte Hospitalsvej 15, DK 2900 Hellerup, Denmark (lise.gether.01@regionh.dk).

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