Original Investigation

Three-Year Patient-Reported Outcomes From Bimekizumab for Plaque Psoriasis

JAMA Dermatology 10.1001/jamadermatol.2025.6055

February 18, 2026 at 11:00 AM EST

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What are the short- and long-term benefits of bimekizumab in outcomes reported by patients with moderate to severe plaque psoriasis?In the phase 3b BE RADIANT randomized clinical trial of 743 patients and open-label extension with 654 patients, bimekizumab improved patient-reported symptoms and health-related quality of life, alongside clinical outcomes, as early as week 4 and through 3 years.These findings support bimekizumab’s durable ability to resolve signs and symptoms and meaningfully improve health-related quality of life for patients with moderate to severe plaque psoriasis.

Corresponding Author: Ronald Vender, MD, Dermatrials Research Inc, Hamilton, ON, Canada (ron.vender@me.com).

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