Observation

Successful Treatment of Pityriasis Rubra Pilaris With Deucravacitinib

JAMA Dermatology 10.1001/jamadermatol.2025.5224

January 21, 2026 at 11:00 AM EST

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This case report describes a woman in her 60s who presented with a 2-month history of rapidly progressive erythematous skin lesions that began on the upper extremities and gradually spread to the buttocks and lower limbs and was diagnosed with pityriasis rubra pilaris.

Corresponding Author: Ping Wang, PhD, Department of Dermatology, Hangzhou Third People’s Hospital, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, West Lake Ave 38, Hangzhou, 310009, People’s Republic of China (dermwang@aliyun.com).

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