Original Investigation

Skin Cancer Surveillance Program for Solid Organ Transplant Recipients

JAMA Dermatology 10.1001/jamadermatol.2025.3890

October 15, 2025 at 11:00 AM EDT

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How does a risk assessment−based skin cancer surveillance program affect screening rates and outcomes among solid organ transplant (SOT) recipients?This retrospective cohort study including 2083 SOT recipients matched with 26 199 nonrecipients found that SOT recipients had a 7.8-fold increased risk of developing posttransplant skin cancer. The skin cancer surveillance program improved screening rates and increased the risk of first-detected skin cancer in higher-risk groups without increasing short-term health care utilization.These findings indicate that risk-stratified surveillance enhanced early skin cancer detection in higher-risk SOT recipients without added burden on health care resources, supporting its utility as a targeted screening approach.

Corresponding Author: David S. Lee, MD, Department of Dermatology, Kaiser Permanente Northern California, 5601 Stoneridge Dr, Pleasanton, CA 94588 (david.s2.lee@kp.org).

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