Research Letter

Finerenone and Blood Pressure in Heart Failure With Mildly Reduced or Preserved Ejection Fraction

JAMA Cardiology 10.1001/jamacardio.2026.2104

July 08, 2026 at 11:00 AM EDT

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This randomized clinical trial analyzes whether finerenone lowers blood pressure and whether its cardiovascular benefits in patients with mildly reduced or preserved ejection fraction heart failure depend on baseline blood pressure or blood-pressure reduction.

Corresponding Author: Scott D. Solomon, MD, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (ssolomon@bwh.harvard.edu).

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