Perspective

Eliminating Unnecessary Animal Testing

JAMA 10.1001/jama.2026.7074

April 20, 2026 at 11:05 AM EDT

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This Perspective reviews the US Food and Drug Administration’s achievements toward eliminating unnecessary animal-based testing and outlines more human-relevant changes for the future.

Corresponding Author: Martin A. Makary, MD, MPH, US Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD 20993 (commissionersoffice@fda.hhs.gov).

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