Perspective

Embracing Bayesian Methods in Clinical Trials

JAMA 10.1001/jama.2026.4179

March 23, 2026 at 11:05 AM EDT

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This Perspective discusses the importance of the US Food and Drug Administration’s draft guidance on the use of bayesian methods in clinical trials because it underscores its commitment to modernizing clinical research.

Corresponding Author: J. Jack Lee, PhD, Department of Biostatistics, University of Texas MD Anderson Cancer Center, 7007 Bertner Ave, Unit 1689, Houston, TX 77030 (jjlee@mdanderson.org).

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