Coronary Computed Tomography Angiography in Prediction of First Coronary Events

Does coronary computed tomography angiography (CCTA) improve risk prediction in primary prevention of coronary events in individuals aged 50 to 64 years at baseline?In a large population-based sample of individuals without established clinical atherosclerotic cardiovascular disease, addition of CCTA data to a model including traditional risk factors and coronary artery calcification score modestly improved prediction of coronary events at 8 years of follow-up. Significant improvement in net correct reclassification was observed in the low-risk group.Information on coronary atherosclerosis from CCTA modestly improved prediction of coronary events beyond traditional risk factors and coronary artery calcium score.

Corresponding Author: Göran Bergström, MD, PhD, Department of Clinical and Molecular Medicine, Sahlgrenska University Hospital, Bruna stråket 16, 41345 Gothenburg, Sweden (goran.bergstrom@hjl.gu.se).

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