Original Investigation

An mHealth (Mobile Health) Intervention for Smoking Cessation in People With Tuberculosis

JAMA 10.1001/jama.2025.20765

December 22, 2025 at 11:00 AM EST

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What is the effectiveness of a mHealth (mobile health) intervention for achieving self-reported continuous tobacco abstinence at 6 months, compared with usual care in people with tuberculosis (TB)?In this randomized clinical trial that included 1080 patients with TB who smoked tobacco, the proportion achieving self-reported continuous tobacco abstinence at 6 months, supported by biochemical verification at 6 months, was significantly higher with mHealth (41.7%) vs with usual care (15.3%).In people with TB who smoke tobacco, the use of an mHealth intervention may be warranted.

Corresponding Author: Kamran Siddiqi, PhD, Hull York Medical School, The University of York, Seebohm Rowntree Building, York, YO10 5DD, United Kingdom (kamran.siddiqi@york.ac.uk).

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