Closed-Loop Insulin Delivery in Type 1 Diabetes in Pregnancy

What is the efficacy of a closed-loop insulin delivery system compared with standard insulin with continuous glucose monitoring in pregnant women with type 1 diabetes?In this multicenter randomized clinical trial of 94 pregnant women with type 1 diabetes, the mean percentage of time spent in the pregnancy-specific glucose range (63-140 mg/dL) from 16 to 34 weeks’ gestation was 65.4% in the closed-loop system group and 50.3% in the standard insulin delivery with continuous glucose monitoring group, a statistically significant difference.The findings support use of this closed-loop system in pregnant women with type 1 diabetes.

Corresponding Author: Lois E. Donovan, MD, University of Calgary, Richmond Road Diagnostic and Treatment Centre, 1820 Richmond Rd SW, Calgary, AB T2T 5C7, Canada (lois.donovan@ahs.ca).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.