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Review

Lung Cancer in Nonsmoking Individuals

JAMA 10.1001/jama.2025.17695

October 20, 2025 at 11:00 AM EDT

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This Review discusses the epidemiology, risk factors, screening, clinical presentation, assessment, diagnosis, treatment, and prognosis of lung cancer in nonsmoking individuals.

Corresponding Author: Benjamin J. Solomon, MBBS, PhD, Department of Medical Oncology, Peter MacCallum Cancer Centre, 305 Grattan St, Parkville, Melbourne, VIC 3000, Australia (ben.solomon@petermac.org).

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