Original Investigation

A Direct-to-Patient Digital Health Program for Lung Cancer Screening

JAMA 10.1001/jama.2025.17281

October 20, 2025 at 11:00 AM EDT

Read the full article

Does a digital health intervention delivered outside a clinical encounter increase lung cancer screening with chest computed tomography (CT) among primary care patients in the US?In a pragmatic randomized trial at 2 academic health systems in the southeastern US, 669 primary care patients were randomized to a digital intervention and 664 to enhanced usual care, which involved informing individuals they met screening criteria and advising them to discuss chest CT screening with their primary care clinician. Patients in the digital intervention group were significantly more likely to complete chest CT at 16 weeks (24.5% vs 17.0%) compared with the control group.A digital health intervention delivered directly to patients modestly increased completion rates of a lung cancer screening CT scan compared with enhanced usual care.

Corresponding Author: David P. Miller, MD, MS, Department of Implementation Science, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157 (dmiller@wakehealth.edu).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.17281?utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102025

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.

Editor's Picks