Review

Prostatitis

JAMA 10.1001/jama.2025.11499

August 11, 2025 at 11:00 AM EDT

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Prostatitis includes acute bacterial prostatitis, chronic bacterial prostatitis, and CP/CPPS, each of which is diagnosed and treated differently. First-line treatments are broad-spectrum antibiotics for acute bacterial prostatitis (such as piperacillin-tazobactam, ceftriaxone, or ciprofloxacin), at least 4 weeks of fluoroquinolones for chronic bacterial prostatitis, and α-blockers for CP/CPPS with urinary symptoms.

Corresponding Author: Minh N. Pham, MD, POB 170 Manning Dr, Chapel Hill, NC 27599-7235 (minh_pham@med.unc.edu).

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