About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This systematic review and meta-analysis of 20 randomized clinical trials compared traditional strength training (lifting and lowering weights under control) with power training (lifting weights fast and lowering under control) for improving physical function in adults age 60 and older.
Authors: Anoop T. Balachandran, Ph.D., of the City University of New York in Flushing, New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.11623)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This survey study found that cost was the most common reason of young adults ages 18 to 25 for not seeking treatment for depression from 2011 to 2019. An increasing number reported inadequate insurance coverage for mental health treatment.
Authors: Wenhua Lu, Ph.D., of the City University of New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.11393)
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Authors: Yuishin Izumi, M.D., Ph.D., of the Tokushima University Graduate School of Biomedical Sciences in Tokushima, Japan, is the corresponding author.
(doi:10.1001/jamaneurol.2022.0901)
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Authors: David A. Asch, M.D., of the University of Pennsylvania, Philadelphia, is the corresponding author.
(doi:10.1001/jamainternmed.2022.1383)
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About The Study: This study estimated racial and ethnic disparities in excess deaths from external causes (homicide, suicide, transportation and drug overdoses) in the United States during the COVID-19 pandemic.
Authors: Mathew V. Kiang, Sc.D., of the Stanford University School of Medicine in Palo Alto, California, is the corresponding author.
(doi:10.1001/jamainternmed.2022.1461)
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About The Study: Researchers updated estimates of the proportion of Alzheimer disease and related dementias in the United States associated with modifiable risk factors and assessed differences by sex, race and ethnicity.
Authors: Roch Nianogo, M.D., Ph.D., of the University of California, Los Angeles, and Deborah E. Barnes, Ph.D., M.P.H., of the University of California, San Francisco, are the corresponding authors.
(doi:10.1001/jamaneurol.2022.0976)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this systematic review and meta-analysis of 81 studies suggest that patients with cancer and SARSCoV-2 infection had a higher risk of death than patients without cancer. Younger age, lung and hematologic cancer were also risk factors associated with poor outcomes from COVID-19.
Authors: Carlo Palmieri, B.Sc., M.B.B.S., Ph.D., of the University of Liverpool in Liverpool, United Kingdom, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.10880)
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EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 10, 2022
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends against screening for chronic obstructive pulmonary disease (COPD) in asymptomatic adults who do not recognize or report respiratory symptoms. Chronic obstructive pulmonary disease is an irreversible reduction of airflow in the lungs. Progression to severe disease can prevent participation in normal activities because of deterioration of lung function. In 2020 it was estimated that approximately 6% of U.S. adults had been diagnosed with COPD. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement is a reaffirmation of its 2016 recommendation statement.
(doi:10.1001/jama.2022.5692)
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Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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About The Study: In a nonurban stroke network in Germany, deployment of a flying intervention team to local stroke centers, compared with patient interhospital transfer to referral centers, was significantly associated with shorter time to endovascular thrombectomy (EVT) for patients with acute ischemic stroke. The findings may support consideration of a flying intervention team for some stroke systems of care, although further research is needed to confirm long-term clinical outcomes and to understand applicability to other geographic settings.
Authors: Gordian J. Hubert, MD, of the TEMPiS telestroke center, Department of Neurology, München Klinik, Academic Teaching hospital of the Ludwig-Maximilians-University in Munich, Germany, is the corresponding author.
(doi:10.1001/jama.2022.5948)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Tyra Fainstad, M.D., of Lowry Internal Medicine in Denver, and Adrienne Mann, M.D., of the Rocky Mountain Regional Veterans Affairs Medical Center in Aurora, Colorado, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2022.10752)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers assessed the adequacy of serial self-performed SARS-CoV-2 rapid antigen detection tests (RADT) performed by untrained persons in the workplace, in terms of the frequency of correct execution of procedural steps and accurate interpretation of the range of possible RADT results.
Authors: Cedric P. Yansouni, M.D., of the Optilab Montreal–McGill University Health Centre in Montreal, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.10559)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: A mailed at-home disposal kit increased self-reported rates of disposal of unused opioids after common surgical procedures in this randomized clinical trial.
Authors: Anish K. Agarwal, M.D., M.P.H., M.S., of the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.10724)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This study of Medicare claims data found that there were immediate declines in the share of patients receiving hospice care with Alzheimer disease and related dementias and a slower growth in use of hospice care by these patients after implementation of Medicare policy changes that aimed to reduce long hospice stays.
Authors: Kan Z. Gianattasio, M.P.P., of the George Washington University Milken Institute School of Public Health in Washington, D.C., is the corresponding author.
(doi:10.1001/jamahealthforum.2022.0900)
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Authors: Julian Bösel, M.D., of Klinikum Kassel in Kassel, Germany, is the corresponding author.
(doi:10.1001/jama.2022.4798)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Ichiei Narita, M.D., Ph.D., of the Niigata University Graduate School of Medical and Dental Sciences in Niigata, Japan, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.10339)
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About The Study: Compared with no endoscopy, initiation of lower gastrointestinal endoscopy before age 50 among women was associated with a reduced risk of colorectal cancer, including colorectal cancer diagnosed before age 55, findings that support guidelines recommending initiation of colorectal cancer screening among women before age 50.
Authors: Mingyang Song, M.D., Sc.D., of the Harvard T.H. Chan School of Public Health in Boston, and Andrew T. Chan, M.D., M.P.H., of Massachusetts General Hospital in Boston, are the corresponding authors.
(doi:10.1001/jamaoncol.2022.0883)
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About The Study: This study of 208,000 women showed annual increases in uterine cancer mortality rates from 2010 to 2017 of 6.7% among Hispanic women, 3.5% among Black women, 3.4% among Asian women and 1.5% among white women, irrespective of histologic subtype or stage at diagnosis.
Authors: Megan A. Clarke, Ph.D., M.H.S., of the National Cancer Institute in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamaoncol.2022.0009)
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About The Study: Researchers examined the financial burden of thyroid cancer and propose a novel framework to guide future research and inform cancer care providers on cost considerations.
Authors: Benjamin James, M.D., M.S., of the Beth Israel Deaconess Medical Center in Boston, is the corresponding author.
(doi:10.1001/jamaoto.2021.0660)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study including 72,000 pediatric encounters for diabetic ketoacidosis, the likelihood of hospital readmission within one year was significantly higher among non-Hispanic Black children compared with Hispanic and non-Hispanic white children with similar measures of neighborhood resources and conditions that influence health.
Authors: Kelly R. Bergmann, D.O., M.S., of Children’s Minnesota in Minneapolis, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.10456)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Aanand D. Naik, M.D., of the Michael E. DeBakey VA Medical Center in Houston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9975)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study used vital statistics data from 2012 to 2019 to project 2020 and 2021 mortality rates and found that alcohol use disorder-related mortality rates in the United States increased among all ages and sexes during the COVID-19 pandemic.
Authors: Yee Hui Yeo, M.D., M.Sc., of Cedars-Sinai Medical Center in Los Angeles, and Fanpu Ji, M.D., Ph.D., of Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2022.10259)
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About The Study: Researchers examined changes in gender-affirming surgery by U.S. region and insurance use during periods when antidiscrimination policies took effect between 2008 and 2017.
Authors: Michael Alperovich, M.D., M.Sc., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.
(doi:10.1001/jamasurg.2022.1053)
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About The Study: This 25-year study that included nearly 4 million Medicare beneficiaries who were alive 30 days after a heart attack found that the rates for 10-year mortality and hospitalization for another heart attack improved steadily over time, but men, Black patients and dual Medicare-Medicaid-eligible patients had higher risks of adverse outcomes.
Authors: Harlan M. Krumholz, M.D., S.M., of Yale New Haven Hospital in New Haven, Connecticut, is the corresponding author.
(doi:10.1001/jamacardio.2022.0662)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This survey study of more than 7,000 smokers ages 16 to 19 found that the menthol cigarette ban in England was associated with a substantial decrease in the proportion who smoke menthol cigarettes, while the rate remained stable among youth in Canada and the United States.
Authors: Katherine A. East, Ph.D., of King’s College London, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.10029)
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Authors: Michael G. Shlipak, M.D., M.P.H., of the San Francisco VA Health Care System, is the corresponding author.
(doi:10.1001/jamainternmed.2022.1449)
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Authors: Arnold R. Gammaitoni, Pharm.D., of Zogenix Inc., in Emeryville, California, is the corresponding author.
(doi:10.1001/jamaneurol.2022.0829)
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Authors: Richard J. McManus, M.B.B.S., Ph.D., of the University of Oxford in Oxford, United Kingdom, is the corresponding author.
(doi:10.1001/jama.2022.4712)
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Authors: Lucy C. Chappell, M.B., B.Chir., Ph.D., of King’s College London, is the corresponding author.
(doi:10.1001/jama.2022.4726)
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About The Study: This retrospective trauma registry study of the University of California, San Diego level 1 trauma center, which receives patients with border wall injuries from San Diego and Imperial counties, examined deaths, injuries and hospital costs after construction of a 30-foot border wall.
Authors: Jay J. Doucet, M.D., of the University of California, San Diego, is the corresponding author.
(doi:10.1001/jamasurg.2022.1885)
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About The Study: Food marketing was associated with increased food intake, choice, preference and purchase requests in children and adolescents in this systematic review and meta-analysis of 96 studies.
Authors: Emma Boyland, Ph.D., of the University of Liverpool in Liverpool, United Kingdom, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.1037)
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About The Study: Coincident with a heightened national discourse on school mental health after the 2018 Parkland, Florida, school shooting, this survey study of more than 165,000 adolescents found that school mental health service use increased in 2019 compared with 2018 and prior years. The increase was most pronounced among Black adolescents and adolescents in low-income families.
Authors: Janet R. Cummings, Ph.D., of Emory University in Atlanta, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.1020)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of more than 25,000 graduating medical students, gay, lesbian and bisexual students had less favorable perceptions of the medical school learning environment and were more likely to experience burnout than their heterosexual peers.
Authors: Caitlin R. Ryus, M.D., M.P.H., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9596)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: A workplace-based guaranteed financial incentive of $1,000 was associated with increased COVID-19 vaccine uptake among employees at a U.S. company.
Authors: Archelle Georgiou, M.D., of Starkey Hearing Technologies in Eden Prairie, Minnesota, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9812)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: Results of this survey study of 7,000 U.S. medical interns suggest that sexual minority interns experience greater depressive symptoms than their heterosexual peers and that this gap widens over the course of training.
Authors: Elena Frank, Ph.D., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.0812)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The first year of the COVID-19 pandemic in the United States was associated with increases in firearm-related incidents, nonfatal injuries and deaths in this analysis that included all 50 states and the District of Columbia.
Authors: Shengzhi Sun, Ph.D., of Capital Medical University in Beijing, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9393)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The preliminary findings from this study suggest that structurally racist redlining policies from the 1930s were associated with decreased current behavioral health clinician availability in redlined communities.
Authors: Clese E. Erikson, M.P.Aff., of George Washington University in Washington, D.C., is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9494)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers examined racial and ethnic disparities in health insurance coverage among Black and Hispanic adults compared with white adults ages 60 to 64. Congress is considering several health policy reforms, including lowering the eligibility age for Medicare from 65 to 60, which could help reduce any disparities in coverage.
Authors: Anna Patterson, B.S.N., R.N., M.P.H., of the University of Pittsburgh Graduate School of Public Health, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9406)
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Authors: Andrew Lawson, M.P.H., of the Ingham Institute for Applied Medical Research in Sydney, is the corresponding author.
(doi:10.1001/jamasurg.2022.0809)
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About The Study: Heart transplant recipients from a single center who were vaccinated against SARS-CoV-2 had significantly lower risk of COVID-19 infection, hospitalization and death compared with unvaccinated recipients.
Authors: Laura L. Peters, D.N.P., F.N.P., of the University of Colorado in Aurora, is the corresponding author.
(doi:10.1001/jamacardio.2022.0670)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers investigated whether residential green space was associated with cognitive function among more than 13,000 middle-age women.
Authors: Marcia P. Jimenez, Ph.D., M.Sc., M.A., of the Boston University School of Public Health, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9306)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this study of 9.5 million women in California living in handgun-free homes, the suicide rate increased substantially after a cohabitant acquired a handgun compared with women whose cohabitants never acquired handguns.
Authors: Matthew Miller, M.D., M.P.H., Sc.D., of Northeastern University in Boston, is the corresponding author.
(10.1001/jamapsychiatry.2022.0793)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers examined whether the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), the reference standard measure of autism spectrum disorder, is systematically biased across race and sex. The findings suggest that the ADOS-2 doesn’t have widespread systematic measurement bias across race or sex. However, the findings raise some concerns around underdetection that warrant further research.
Authors: Luther G. Kalb, Ph.D., M.H.S., of the Kennedy Krieger Institute in Baltimore, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.9498)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study of surveillance data from the Vaccine Safety Datalink that included 15.1 million doses of COVID-19 vaccines investigated cases and incidence of Guillain-Barré syndrome (GBS) following vaccination and assessed the risk of GBS after vaccination with the Janssen, Pfizer-BioNTech or Moderna COVID-19 vaccines.
Authors: Nicola P. Klein, M.D., Ph.D., of Kaiser Permanente Northern California in Oakland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.8879)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Black patients were less likely to be treated with proton beam therapy (PBT) than white patients, especially for cancers for which PBT is recommended over photon-based radiation therapy, according to the results of this study that included 5.2 million patients.
Authors: Leticia M. Nogueira, Ph.D., M.P.H., of the American Cancer Society in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.8970)
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Authors: Yuan Shi, M.D., Ph.D., of Chongqing Medical University in Chongqing, China, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.0710)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this study of 330 family members of patients admitted to the intensive care unit (ICU) with COVID-19, family members had significant symptoms of posttraumatic stress disorder (PTSD) three months after patients’ admissions. Hispanic ethnicity and female gender were associated with higher measures of PTSD symptoms. Family members with higher measures of symptoms reported more distrust of practitioners.
Authors: Timothy Amass, M.D., Sc.M., of the University of Colorado School of Medicine in Aurora, is the corresponding author.
(doi:10.1001/jamainternmed.2022.1118)
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About The Study: Researchers examined the pattern of suicides from 2015 through 2020 among youth ages 10 to 19 in 14 states.
Authors: Marie-Laure Charpignon, M.Sc., of Boston Children’s Hospital, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.0515)
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About The Study: There were significant reductions in the prevalence of self-reported cigarette smoking among U.S. adults with major depressive episode, substance use disorder or both between 2006 and 2019 in this study that included nearly 560,000 participants.
Authors: Wilson M. Compton, M.D., M.P.E., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jama.2022.4790)
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EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 26, 2022
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) has updated and changed its recommendation on low-dose aspirin use to prevent cardiovascular disease (CVD). The USPSTF now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults 60 years or older.The decision to initiate low-dose aspirin use for the primary prevention of CVD in adults ages 40 to 59 years who have a 10% or greater 10-year CVD risk should be an individual one. Evidence indicates that the net benefit of aspirin use in this group is small. Those who are not at increased risk for bleeding and are willing to take low-dose aspirin daily are more likely to benefit. The USPSTF also has concluded the evidence is unclear whether aspirin use reduces the risk of colorectal cancer incidence or death. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation replaces the 2016 USPSTF recommendation on aspirin use to prevent CVD and colorectal cancer.
(doi:10.1001/jama.2022.4983)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Almudena Carneiro-Barrera, Ph.D., of the University of Granada in Granada, Spain, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.8212)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This modeling study estimates that COVID-19 vaccination in California prevented more than 1.5 million COVID-19 cases, 72,000 hospitalizations and 19,000 deaths during the first 10 months of vaccination.
Authors: Nathan C. Lo, M.D., Ph.D., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.8526)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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