Participation of Patients From Racial, Ethnic Minority Groups in Phase 1 Cancer Drug Development Trials

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 3, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.30884?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110322

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study compared the proportions of racial and ethnic groups in 221 phase 1 clinical trials of drugs for metastatic cancer from 2000 to 2018 with population-based cancer registry data and found worsening disparities over time in the accrual of patients from racial and ethnic minority groups. These findings may represent widening inequalities in access to trial sites and worsening systemic biases. More efforts are needed to diversify phase 1 cancer drug trials to improve equity in access to new treatments and to ensure that safety and efficacy findings from early drug trials are generalizable across populations.

Authors: C. Jillian Tsai, M.D., Ph.D., of the Princess Margaret Cancer Centre in Toronto, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.30884)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Complexity, Challenges of the Clinical Diagnosis, Management of Long COVID

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 3, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.40332?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110322

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This analysis of the health records of a random national sample of 200 veterans who had experienced SARS-CoV-2 infection and who had at least one diagnostic code for long COVID highlights the complexity of diagnosing long COVID in clinical settings and the challenges of caring for patients who have or are suspected of having this condition.

Authors: Ann M. O’Hare, M.A., M.D., of the VA Puget Sound Health Care System in Seattle, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.40332)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Visual Abstract: Electroacupuncture vs Sham in Postoperative Ileus Treatment After Laparoscopic Surgery for Colorectal Cancer

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 2, 2022

Media advisory: The full study and commentary are linked to this news release. A visual abstract is below.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.5674?guestAccessKey=98951447-6210-446a-84d3-eae886061982&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110222

 

Visual Abstract

Authors: Cun-Zhi Liu, Ph.D., of the Beijing University of Chinese Medicine in Beijing, and Ying-Chi Yang, Ph.D., of Beijing Friendship Hospital Affiliated to Capital Medical University in Beijing, are the corresponding authors.

 

(doi:10.1001/jamasurg.2022.5674)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Mental Health Care Utilization Among Children, Adolescents With a Firearm Injury

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.5299?guestAccessKey=c70dacae-cf22-4f5a-bb4b-c332029f0f74&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110222

Estimating Savings Opportunities From Therapeutic Substitutions of High-Cost Generic Medications

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 2, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39868?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110222

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this analysis of the top 1,000 generics in Colorado’s all-payer claims database in 2019, researchers identified 45 high-cost products that had lower-cost therapeutic alternatives of same clinical value. Overall, high-cost generics were 15.6 times more expensive than their therapeutic alternatives (median values). If the lower-cost alternatives had been used, total spending would have been reduced by 88%. Substitution of high-cost generics may provide a simple pathway to offer the same therapeutic benefit at lower cost to patients and insurers.

Authors: Mariana P. Socal, M.D., Ph.D., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.39868)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

COVID-19 Case Investigation, Contact Tracing in New York City

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 2, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39661?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110222

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Researchers describe the establishment, scaling, and maintenance of Trace, New York City’s COVID-19 contact tracing program and provide data on outcomes during its first 17 months.

Authors: Kathleen Blaney, M.P.H., R.N., of the New York City Department of Health and Mental Hygiene in Queens, New York, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.39661)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Gonadotropin-Releasing Hormone Analogue Use With Subsequent Use of Gender-Affirming Hormones Among Transgender Adolescents

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39758?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110122

Estimated Deaths Attributable to Excessive Alcohol Use Among US Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 1, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39485?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110122

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this cross-sectional study suggest that between 2015 and 2019 an estimated 1 in 8 total deaths among U.S. adults ages 20 to 64 were attributable to excessive alcohol use, including 1 in 5 deaths among adults ages 20 to 49. The number of premature deaths could be reduced with increased implementation of evidenced-based, population-level alcohol policies, such as increasing alcohol taxes or regulating alcohol outlet density.

Authors: Marissa B. Esser, Ph.D., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.39485)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Hormone Therapy With Depression During Menopause

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 1, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39491?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110122

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study of women in Denmark followed up from age 45 suggest that systemically administered (oral or transdermal) hormonal therapy before and during menopause is associated with higher risk of depression, especially in the years immediately after initiation, whereas locally administered (intravaginal or intrauterine) hormonal therapy is associated with lower risk of depression for women 54 years or older.

Authors: Merete Osler, M.D., Ph.D., D.M.Sc., of the Bispebjerg and Frederiksberg Hospitals in Frederiksberg, Denmark, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.39491)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Estimated Travel Time, Access to Abortion Facilities Before, After Dobbs v Jackson Women’s Health Decision

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 1, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.20424?guestAccessKey=70c1bc40-5cc0-4bcf-a73d-a5b9b26ccf01&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

About The Study: In this analysis, estimated travel time to abortion facilities in the U.S. was significantly greater in the post-Dobbs period after accounting for the closure of abortion facilities in states with total or 6-week abortion bans compared with the pre-Dobbs period, during which all facilities providing abortions in 2021 were considered active.

Authors: Yulin Hswen, Sc.D., of the University of California, San Francisco, is the corresponding author.

 

(doi:10.1001/jama.2022.20424)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Texas’ Abortion Ban With the Number of Facility-Based Abortions in Texas, Surrounding States

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 1, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.20423?guestAccessKey=632f2f19-ea02-46ff-814b-a95d7b371568&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

About The Study: Among a sample of abortion facilities, the 2021 Texas law banning abortion in early pregnancy (SB 8) was significantly associated with a decrease in the documented total of facility-based abortions in Texas and obtained by Texas residents in surrounding states in the first month after implementation compared with the previous month. Over the 6 months following SB 8 implementation, the percentage of out-of-state abortions among Texas residents obtained at 12 or more weeks of gestation significantly increased.

Authors: Kari White, Ph.D., M.P.H., of the University of Texas at Austin, is the corresponding author.

 

(doi:10.1001/jama.2022.20423)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Stroke, Cerebrovascular Pathologies With Scam Susceptibility in Older Adults

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2022.3711?guestAccessKey=70307683-4dba-4863-a387-fe3889252cb4&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=103122

Health Care Access and Reproductive Rights

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 1, 2022

 

About This Issue: This issue of JAMA includes original research and eight scholarly Viewpoints that provide data and perspective about abortion care and the larger context of evidence-based health care. In addition, there is an editorial, Medical News articles and a Patient Page on medication abortion. Also included in this news release are related articles from the JAMA Network.

 

The full articles are linked to this news release. The links below the titles of the articles will provide readers free access to the full-text article at the embargo time.

 

 

JAMA 

Original Research 

Associations of Unintended Pregnancy With Maternal and Infant Health Outcomes 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.19097?guestAccessKey=6d5537a7-b4df-442a-ae21-d59617a7a2ea&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Adverse Maternal and Delivery Outcomes in Children and Very Young (Age ≤13 Years) US Adolescents Compared With Older Adolescents and Adults 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.18340?guestAccessKey=224963f0-8409-4925-b85f-87dbc2f6c0d9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Requests for Self-managed Medication Abortion Provided Using Online Telemedicine in 30 US States Before and After the Dobbs v Jackson Women’s Health Organization Decision 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.18865?guestAccessKey=0bf9b1b5-f43a-4a80-9cd6-294fac7370cf&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Editorial 

Health Care Access and Reproductive Rights 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.19172?guestAccessKey=2b6b2fe5-334a-4676-97d3-800929283960&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Viewpoints 

Advancing Birth Equity in a Post-Dobbs US 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.19468?guestAccessKey=b74374fb-b2a2-47ff-991e-5a420759aa34&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

The Challenge of Emergency Abortion Care Following the Dobbs Ruling 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.17197?guestAccessKey=962dbb2a-7690-49c7-8eb2-cc9a9d160f2b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Self-managed Abortion in the US 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.19057?guestAccessKey=84caf7c0-0ff4-4fc0-bb7a-0dbd81c3d868&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Legal Risks and Ethical Dilemmas for Clinicians in the Aftermath of Dobbs 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.18453?guestAccessKey=d3101b78-3d8a-4101-9ebd-3e2a4ab240a7&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Implications of the Dobbs Decision for Medical Education – Inadequate Training and Moral Distress 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.19544?guestAccessKey=54d58800-a8e1-4698-915e-498128ffe44a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

The Shift From Criminalization to Legalization of Abortion in Argentina 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.18971?guestAccessKey=f2e1285d-1d40-424c-abb1-067a814e0e19&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Confronting the Medical Community’s Complicity in Marginalizing Abortion Care 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.18328?guestAccessKey=28459bb2-ad78-4762-8458-b72f0c1fdc3a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Interoperability in a Post-Roe Era – Sustaining Progress While Protecting Reproductive Health Information 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.17204?guestAccessKey=fd35e0ad-beff-4c3a-b6c0-80543a8ba27b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Medical News 

Dobbs Decision Threatens Full Breadth of Ob-Gyn Training 

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.13662?guestAccessKey=00fa5e30-5dab-4578-aab1-9aec6827d1b2&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

JAMA Network Open 

Original Research  

Changes in the Clinical Workforce Providing Contraception and Abortion Care in the US, 2019-2021 

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39657?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110122 

 

JAMA Surgery 

Viewpoint 

The Dobbs v Jackson Women’s Health Organization Supreme Court Decision – Concerns, Challenges, and Consequences for Health Care 

https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.5714?guestAccessKey=4e0dd68f-7197-4227-b10a-0bd2abafbc4e&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

Editorial

The A Word – Our Collective Scarlet Letter

https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.6638?guestAccessKey=b850a26c-ad53-4d19-950b-72b304f51897&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Previously Released  

Medical News 

Threats to Evidence-Based Care With Teratogenic Medications in States With Abortion Restrictions 

Treating Cancer in Pregnant Patients After Roe v Wade Overturned 

 

JAMA Patient Page 

Medication Abortion

 

Editor’s Note: Please see the articles for additional information, including author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. 

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations

Association Between Price, Measures of Efficacy for Oncology Drugs Approved by FDA

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, OCTOBER 31, 2022

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2022.4924?guestAccessKey=a0b37add-e1a5-4e8a-9b6b-c2eab0e59eaf&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=103122

 

About The Study: This study examined Food and Drug Administration (FDA) anticancer drug approvals in recent years and evaluated if an association exists between their cost and efficacy.

Authors: Vinay Prasad, M.D., M.P.H., of the University of California, San Francisco, is the corresponding author.

 

(doi:10.1001/jamainternmed.2022.4924)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

USPSTF Recommendation Statement on Hormone Therapy for Prevention of Postmenopausal Conditions

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 1, 2022

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time and all USPSTF articles remain free indefinitely https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.18625?guestAccessKey=4927b8e8-df65-4c08-a3e1-7c0d5ab6b4ee&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110122

 

Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends against the use of combined estrogen and progestin for the primary prevention of chronic conditions in postmenopausal persons and against the use of estrogen alone for the primary prevention of chronic conditions in postmenopausal persons who have had a hysterectomy. This recommendation applies to asymptomatic, postmenopausal persons who are considering hormone therapy for the primary prevention of chronic medical conditions. The prevalence and incidence of most chronic diseases (such as cardiovascular disease, cancer, osteoporosis, and fracture) increase with age, and U.S. persons who reach menopause are expected on average to live more than another 30 years. However, the excess risk for chronic conditions that can be attributed to menopause alone is uncertain. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation is consistent with its 2017 statement on hormone therapy for the primary prevention of chronic conditions in postmenopausal women.

 

(doi:10.1001/jama.2022.18625)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email mediarelations@jamanetwork.org.

State-Issued COVID-19 Vaccine Mandates, Rates of Vaccine Administration

About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.3810?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102822

Lobbying Expenditures in the Health Care Sector, 2000-2020

About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.3801?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102822

Analysis of Medicaid Expansion and Access to Prenatal Care Among Immigrant vs US-Born Women

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, OCTOBER 28, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.39264?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102822

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this study suggest that exclusions from Medicaid eligibility based on immigration status may be associated with increased health care disparities among some immigrant groups. This finding has relevance to current policy debates regarding Medicaid coverage during and outside of pregnancy.

 Authors: Teresa Janevic, Ph.D., M.P.H., of the Icahn School of Medicine at Mount Sinai in New York, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.39264)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Trends in Racial, Ethnic Disparities in Barriers to Timely Medical Care

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, OCTOBER 28, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.3856?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102822

About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: The findings of this study of survey data including 590,000 adults suggest that barriers to timely medical care in the U.S. increased for all population groups from 1999 to 2018, with associated increases in disparities among race and ethnicity groups. Interventions beyond those currently implemented are needed to improve access to medical care and to eliminate disparities among race and ethnicity groups.

Authors: Harlan M. Krumholz, M.D., S.M., of Yale New Haven Hospital in New Haven, Connecticut, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2022.3856)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Serious Adverse Event Reporting in Cancer Clinical Trials During the Pandemic

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2022.4919?guestAccessKey=440e57f5-0e8a-4e92-b1fe-77c4de070477&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102722

Identification of Factors Associated With Development of Optic Disc Edema During Spaceflight

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2022.4396?guestAccessKey=5ce38ac0-b13b-4853-b510-99400ea022be&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102722

Hospital Markup in Head and Neck Cancer Surgery

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, OCTOBER 27, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2022.3340?guestAccessKey=13397972-351e-4fac-b840-60ed8458c3d4&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102722

 

About The Study: Researchers found in this study of 150,000 patients wide variation in hospital markup for head and neck cancer surgery, with a 4-fold increase in charges relative to costs in 25% of hospitals. The highest markups were found in for-profit hospitals in moderately concentrated and concentrated markets. These data suggest that greater transparency is needed to address disparities in hospital pricing.

Authors: Christine G. Gourin, M.D., M.P.H., of Johns Hopkins Medical Institutions in Baltimore, is the corresponding author.

 

(doi:10.1001/jamaoto.2022.3340)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Prevalence of Long COVID Symptoms Among US Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, OCTOBER 27, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38804?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102722

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of more than 16,000 individuals, 15% with a prior positive COVID-19 test reported symptoms lasting longer than two months. Those who completed a primary vaccination series prior to infection were less likely to report long COVID symptoms. The risk varied among individual subgroups.

Authors: Roy H. Perlis, M.D., M.Sc., of Massachusetts General Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.38804)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Recurrence of Symptoms Following a 2-Day Symptom Free Period in Patients With COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, OCTOBER 27, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38867?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102722

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Using daily symptoms data from a prospective trial involving 158 participants, researchers found the natural history of untreated COVID-19 was variable and undulating. Over one-third of participants who experienced symptom resolution for at least two consecutive days within the first 4 to 5 weeks of COVID-19 symptoms reported recurrent symptoms. 

Authors: Davey M. Smith, M.D., M.A.S., of the University of California San Diego in La Jolla, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.38867)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

BMI Trajectories Preceding Incident Mild Cognitive Impairment, Dementia

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2022.3446?guestAccessKey=b3654376-e3da-4841-b488-98c00898d611&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102622

Sex Differences in Mental Health Problems, Psychiatric Hospitalization in Autistic Young Adults

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2022.3475?guestAccessKey=5791112f-1281-4e29-bcda-a2c0d90a1a1d&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102622

Effects of Low-Carbohydrate Dietary Intervention on A1C

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, OCTOBER 26, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38645?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102622

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this 6-month randomized clinical trial that included 150 adults, a low-carbohydrate diet intervention led to larger reductions in hemoglobin A1c (HbA1c) than usual diet among adults with elevated untreated HbA1c, though the study was unable to evaluate its effects independently of weight loss. This diet, if sustained, might be a useful dietary approach for preventing and treating type 2 diabetes, but more research is needed.

Authors: Kirsten S. Dorans, Sc.D., of the Tulane University School of Public Health and Tropical Medicine in New Orleans, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.38645)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Evaluation of Automated Text Messaging to Reduce Use of Health Care Resources After Hospital Discharge

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, OCTOBER 26, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38293?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102622

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this cohort study suggest that an automated texting program to support primary care patients after hospital discharge was associated with significant reductions in use of acute care resources. This patient-centered approach may serve as a model for improving post-discharge care.

Authors: Eric Bressman, M.D., M.S.H.P., of the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.38293)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Differences in Clinical Treatment, Outcomes by Race Among Veterans Hospitalized With COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, OCTOBER 25, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38507?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102522

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study that included 43,000 veterans suggest that Black veterans hospitalized with COVID-19 were less likely to be treated with evidence-based COVID-19 treatments, including systemic steroids, remdesivir, and immunomodulatory drugs. Differences in care were partially explained by within- and between-hospital differences and underscore the need for a comprehension approach to minimize racial variation in COVID-19 care.

Authors: Florian B. Mayr, M.D., M.P.H., of the VA Pittsburgh Healthcare System in Pittsburgh, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.38507)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Variation in Research Experiences, Publications During Medical School by Sex, Race, Ethnicity

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, OCTOBER 25, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38520?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102522

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Researchers found in this study of 31,000 medical school graduates a significant disparity in publication rates across sex and race and ethnicity, with women and Black and Hispanic students reporting lower publication rates compared with men and white students. These findings suggest that inequities in the physician-scientist workforce began early in training, as exposure to research and research productivity are critical for a successful career as a physician-scientist.

Authors: Mytien Nguyen, M.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.38520)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Prostate-Specific Antigen Screening Rates With Subsequent Metastatic Prostate Cancer Incidence at Veterans Health Administration Facilities

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2022.4319?guestAccessKey=64418a55-4d5c-4a34-aae3-4b74ebe425c2&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102422

Visual Abstract: Effect of Wearing a Face Mask on Hand-to-Face Contact by Children in a Simulated School Environment

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, OCTOBER 24 2022

Media advisory: The full study is linked to this news release. A visual abstract is below.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.3833?guestAccessKey=4df403f1-1ffe-4a86-9b91-088e2adeca51&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102422

 

Visual Abstract

Authors: Michelle Science, M.D., M.Sc., of the Hospital for Sick Children in Toronto, is the corresponding author.

(doi:10.1001/jamapediatrics.2022.3833)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Spike-Specific T Cells With Relative Protection From Subsequent SARS-CoV-2 Omicron Infection in Young Children

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.3868?guestAccessKey=0f130c51-ba03-420e-b544-2ef6abbf3c70&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102422

Estimating the Prevalence of Dementia, Mild Cognitive Impairment in the US

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, OCTOBER 24, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2022.3543?guestAccessKey=019682c2-546b-47ef-918a-c881c1fae686&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102422

 

About The Study: Using a comprehensive neuropsychological test battery, researchers found in this nationally representative cross-sectional study of nearly 3,500 individuals age 65 and older that 10% were classified as having dementia and 22% as having mild cognitive impairment (MCI). The results indicated a disproportionate burden of dementia among older Black adults, of MCI among older Hispanic adults, and of both among people with lower educational attainment.

Authors: Jennifer J. Manly, Ph.D., of the Columbia University Irving Medical Center in New York, is the corresponding authors.

 

(doi:10.1001/jamaneurol.2022.3543)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Video Gaming With Cognitive Performance Among Children

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, OCTOBER 24, 2022

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.35721?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102422

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Compared with non-video gamers, video gamers were found to exhibit better cognitive performance involving response inhibition and working memory as well as altered blood oxygen level-dependent signal in key regions of the cortex responsible for visual, attention, and memory processing in this study involving 2,200 children. The findings are consistent with videogaming improving cognitive abilities that involve response inhibition and working memory and altering their underlying cortical pathways.

Authors: Bader Chaarani, Ph.D., of the University of Vermont in Burlington, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.35721)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Experiences With Prenatal Care Delivery Reported by Black Patients With Low Income and by Health Care Workers

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, OCTOBER 24, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38161?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102422

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this qualitative study of low-income, Black pregnant people in Detroit and the health care workers who care for them, prenatal care delivery failed to meet many patients’ needs. Participants reported that an ideal care delivery model would include comprehensive, integrated services across the health care system, expanding beyond medical care to also include patients’ social needs and preferences.

Authors: Alex Friedman Peahl, M.D., M.Sc., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.38161)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Visual Abstract: Effect of a Novel Brief Motivational Intervention for Alcohol-Intoxicated Young Adults in the Emergency Department

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, OCTOBER 21, 2022

Media advisory: The full study is linked to this news release. A visual abstract is below.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.37563?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102122

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

Visual Abstract

Authors: Jacques Gaume, Ph.D., of the Lausanne University Hospital and University of Lausanne in Lausanne, Switzerland, is the corresponding author.

(doi:10.1001/jamanetworkopen.2022.37563)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Association of Hospice Payer With Concurrent Receipt of Hospice and Dialysis Among Veterans With End-stage Kidney Disease

About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.3708?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102122

Variation in HPV Vaccination Effectiveness by Age at Vaccination

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, OCTOBER 21, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.38041?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102122

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Researchers assessed the status and timing of human papillomavirus (HPV) vaccination as self-reported by female participants in this survey study.

Authors: Didem Egemen, Ph.D., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.38041)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Assessment of Strategies Used in Hospitals to Address Social Needs During Pandemic

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, OCTOBER 21, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.3764?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102122

About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: The results of this survey study suggest that rural hospitals, critical access hospitals, and safety-net hospitals are not doing more and, in some cases, are engaging in fewer strategies to address the social determinants of health of their vulnerable populations, especially regarding community partnerships. This finding may be attributable to limited financial resources, workforce constraints, limited community resources and institutional partnerships, and lack of incentives.

Authors: Jose F. Figueroa, M.D., M.P.H., of the Harvard T.H. Chan School of Public Health in Boston, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2022.3764)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19

JAMA

EMBARGOED FOR RELEASE: 1:45 P.M. (ET), FRIDAY, OCTOBER 21, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.18590?guestAccessKey=57cc9ab2-90d5-4657-820e-5f19760649ba&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102122

 

About The Study: Among outpatients with mild to moderate COVID-19, treatment with ivermectin, compared with placebo, did not significantly improve time to recovery in this trial that enrolled more than 1,500 participants in the United States. A lack of treatment effect was also seen for secondary clinical outcomes including hospitalization, death, or acute care visits. These findings do not support the use of ivermectin in patients with mild to moderate COVID-19.

Authors: Susanna Naggie, M.D., M.H.S., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.

 

(doi:10.1001/jama.2022.18590)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Geographic Analysis of Google Characterizations of Who Is an ‘Eye Doctor’ Across the US

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2022.4343?guestAccessKey=8a2151d1-3f23-4337-ba6f-63eaa552b3e8&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102022

Trends in Emergency Department Use After Sexual Assault

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, OCTOBER 20, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.36273?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102022

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study of emergency department visits made annually from 2006 through 2019 found a significant increase in sexual assault emergency department visits, outpacing the growth of law enforcement reporting. Concurrently, there was a significant decrease in admission rates for sexual assault. These data can inform policies and the programming needed to support this vulnerable population.

Authors: Erica E. Marsh, M.D., M.S.C.I., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.36273)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Analysis of Residential Segregation, Racial, Ethnic Disparities in Severe Maternal Morbidity Before, During Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, OCTOBER 20, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.37711?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102022

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Living in high-segregated Black communities in South Carolina was associated with racial and ethnic severe maternal morbidity disparities according to the results of this study including 166,000 women with childbirths from January 2018 to June 2021. During the COVID-19 pandemic, Black versus white disparities persisted with no signs of widening gaps, whereas Hispanic versus white disparities were exacerbated. Policy reforms on reducing residential segregation or combating the corresponding structural racism are warranted to help improve maternal health.

Authors: Peiyin Hung, Ph.D., M.S.P.H., of the University of South Carolina Arnold School of Public Health in Columbia, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.37711)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Estimates of 1-Year Mortality After Major Surgery Among Older Adults

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, OCTOBER 19, 2022

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.5155?guestAccessKey=46e8dbf8-35db-4ffe-b9d0-5635ed6154a0&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=101922

 

About The Study: In this analysis of 1,193 major surgeries among community-living adults age 65 or older, the population-based estimate of 1-year mortality after major surgery was 13.4% but was 3-fold higher for non-elective than elective procedures. Mortality was considerably elevated among older persons who were frail or who had probable dementia, highlighting the potential prognostic value of geriatric conditions after major surgery.

Authors: Thomas M. Gill, M.D., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.

 

(doi:10.1001/jamasurg.2022.5155)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Defining Essential Surgery During the Pandemic Response

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, OCTOBER 19, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.3944?guestAccessKey=0049526e-d578-4770-96ae-dbd20db152f9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=101922

 

About The Study: Researchers compared the volume of performed surgical procedures classified as essential, urgent, and nonurgent before and after elective surgeries were restricted during the COVID-19 pandemic in the United States.

Authors: Sherry M. Wren, M.D., of Stanford-Surgery Policy Improvement Research & Education Center in Stanford, California, is the corresponding author.

 

(doi:10.1001/jamasurg.2022.3944)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Comparative Safety of Pfizer-BioNTech COVID-19 Vaccine vs Non–SARS-CoV-2 Vaccines in Children Younger Than Age 5

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, OCTOBER 18, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.37140?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=101822

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The symptoms reported after administration of the Pfizer-BioNTech COVID-19 vaccine were comparable overall to those for approved non–SARS-CoV-2 vaccines in this study including 7,800 children younger than age 5. The data may be used together with prospective licensure studies of BNT162b2 efficacy and safety and could help guide expert recommendations about BNT162b2 vaccinations in this age group.

Authors: Cho-Ming Chao, M.D., Ph.D., of the University of Rostock in Rostock, Germany, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.37140)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Visual Abstract: Effect of Implementation Facilitation to Promote Adoption of Medications for Addiction Treatment in US HIV Clinics

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, OCTOBER 17, 2022

Media advisory: The full study is linked to this news release. A visual abstract is below.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.36904?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=101722

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

Visual Abstract

Authors: E. Jennifer Edelman, M.D., M.H.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.

(doi:10.1001/jamanetworkopen.2022.36904)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Incidence of Kawasaki Disease Before, After COVID-19 Pandemic in Japan

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.3756?guestAccessKey=15ccbe74-5ba6-4107-b059-a6460b95dae1&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=101722

Role of Autism Diagnostic Observation Schedule in Autism Spectrum Disorder Diagnosis in Young Children

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.3605?guestAccessKey=d3f6c637-1d48-48a8-a3f1-0f14c25a6acc&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=101722

Gender-Affirming Chest Reconstruction Among Transgender and Gender-Diverse Adolescents

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.3595?guestAccessKey=a85ea7b3-150e-42d8-b9b0-34000f2d681e&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=101722

Association of Adequacy of Broadband Internet Service With Access to Primary Care in Veterans Health Administration Before, During Pandemic

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.36524?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=101722