Complications, Adverse Drug Events, High Costs, Disparities in Multisystem Inflammatory Syndrome in Children vs COVID-19

JAMA Network Open


Media advisory: The full study and commentary are linked to this news release.

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About The Study: In this study of 4,100 multisystem inflammatory syndrome in children (MIS-C) hospitalizations in 2021, MIS-C was more common and severe than previously reported, with more racial disparities in outcomes than were seen in patients with COVID-19. The findings of this study suggest that relying on mean outcomes for MIS-C from past studies can be misleading, since outcomes and disparities varied widely with the number of multiorgan dysfunctions.  

Authors: William Encinosa, Ph.D., of the Agency for Healthcare Research and Quality in Rockville, Maryland, is the corresponding author. 



Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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