Original Investigation

Prior Sexual Violence, PTSD Symptoms, and Recovery Trajectories After New Trauma

JAMA Psychiatry 10.1001/jamapsychiatry.2026.2219

July 29, 2026 at 11:00 AM EDT

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Do trajectories of posttraumatic stress disorder (PTSD) symptom recovery differ based on history of sexual violence? In this longitudinal case-control study of 2423 patients admitted to emergency departments across the US, participants with a history of sexual violence demonstrated significantly elevated symptoms of PTSD and slower symptom recovery compared with those without a history of sexual trauma, even after controlling for earlier nonsexual trauma exposure. Findings suggest that earlier sexual violence may shape how people respond to subsequent nonsexual traumas.

Corresponding Author: Emily J. Mellen, PhD, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA 02478 (emily.mellen@tuftsmedicine.org).

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