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Maternal RSVpreF Vaccine Effectiveness Against Respiratory Syncytial Virus in Hospitalized Infants

JAMA Pediatrics 10.1001/jamapediatrics.2026.3391

August 17, 2026 at 11:00 AM EDT

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Findings in this case-control study demonstrate high year-round effectiveness of RSVpreF vaccination against RSV-associated hospitalization in infants 6 months of age or younger in the first year following introduction in Australia, with the highest VE observed in the earliest age intervals. Future analyses with larger sample sizes will evaluate VE among additional subgroups.

Corresponding Author: Ushma Wadia, MBBS, The Kids Research Institute Australia, 15 Hospital Ave, Nedlands, WA 6009, Australia (ushma.wadia@thekids.org.au).

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