Original Investigation

High Pesticide Exposure Events and Self-Reported and Measured Olfactory Dysfunction

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2026.2605

September 10, 2026 at 11:00 AM EDT

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This survey study found that HPEEs were associated with subjective reports of olfactory loss among farmers but not with their measured smell identification. These findings underscore the importance of incorporating both objective and subjective measures of olfaction in epidemiologic research.

Corresponding Authors: Brenda L. Plassman, PhD, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2400 Pratt St, 6th Fl, Office 6012, Box 102505, Durham, NC 27705 (brenda.plassman@duke.edu); Honglei Chen, PhD, Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, 909 Wilson Rd, Room B601, East Lansing, MI 48824 (hchen@epi.msu.edu).

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