Original Investigation

Compartment-Specific Recurrence in Medullary Thyroid Cancer

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2026.2597

September 03, 2026 at 11:00 AM EDT

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This study found that, in MTC, the most frequent sites of recurrence were the ipsilateral central and lateral neck. Contralateral central neck recurrence was uncommon; however, our wide CIs preclude definitive conclusions about the benefit of contralateral pCND, and larger studies are warranted.

Corresponding Author: James X. Wu, MD, UCLA David Geffen School of Medicine, 10833 LeConte Ave, CHS 72-228, Los Angeles, CA 90095 (jameswu@mednet.ucla.edu).

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