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Geyserlike OCT Sign in Transthyretin Amyloidosis

JAMA Ophthalmology 10.1001/jamaophthalmol.2026.1576

May 28, 2026 at 11:00 AM EDT

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This case report discusses a diagnosis of transthyretin amyloidosis after an unusual finding on optical coherence tomography (OCT) in a woman aged 52 years with dense vitreous opacities.

Corresponding Author: Luca De Simone, MD, Ocular Immunology Unit, Azienda USL-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, Italy (luca.desimone@ausl.re.it).

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