Research Letter

Reticular Pseudodrusen and Cardiovascular Disease or Related Mortality in AREDS and AREDS2

JAMA Ophthalmology 10.1001/jamaophthalmol.2026.1525

May 21, 2026 at 11:00 AM EDT

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This post hoc analysis of the AREDS and AREDS2 trials investigates potential associations between reticular pseudodrusen and cardiovascular disease events or related mortality.

Corresponding Author: Emily Y. Chew, MD, Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, 10 Center Dr, Room 10D45, Bethesda, MD 20892-2510 (echew@nei.nih.gov).

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