Original Investigation

Cancer Biologics Utilization After Biosimilar Entry and Financial Implications For Payers and Patients

JAMA Oncology 10.1001/jamaoncol.2026.3128

August 27, 2026 at 11:00 AM EDT

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The results of this cohort study suggest that biosimilar entry was associated with lower ASP and reduced market share for reference biologics in oncology. Market competition introduced by biosimilars was also associated with lowered payer costs and reduced patient financial burden.

Corresponding Author: Ya-Chen Tina Shih, PhD, 650 Charles Young Drive South, A2-125 CHS, BOX 956900. Los Angeles, CA 90095-6900 (tinashih@mednet.ucla.edu).

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