Original Investigation

Tissue-Free vs Tumor-Informed ctDNA Assays for Molecular Residual Disease Detection in Early Triple Negative Breast Cancer

JAMA Oncology 10.1001/jamaoncol.2026.2833

August 13, 2026 at 11:00 AM EDT

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This prognostic study compares tissue-free circulating tumor DNA analysis to tissue-free assay with tumor-informed assay results for estimating recurrence in patients with triple negative breast cancer.

Corresponding Author: Nicholas C. Turner, MD, PhD, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, 237 Fulham Rd, London SW7 3RP, United Kingdom (nick.turner@icr.ac.uk).

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