Research Letter

GLP-1 Receptor Agonists and Obesity-Related Cancer by Diabetes Severity

JAMA Network Open 10.1001/jamanetworkopen.2026.41869

November 03, 2026 at 11:00 AM EST

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This cohort study examines the associations between glucagon-like peptide-1 receptor agonist (GLP-1 RA) initiation and obesity-related cancer incidence across active comparators and baseline type 2 diabetes severity.

Corresponding Author: Jesús Gibran Hernández-Pérez, PhD, MS, Peter O’Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 (JesusGibran.HernandezPerez@UTSouthwestern.edu).

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