Original Investigation

RELAX Perinatal Digital Intervention to Prevent Increasing Anxiety

JAMA Network Open 10.1001/jamanetworkopen.2026.40518

November 04, 2026 at 11:00 AM EST

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In this randomized clinical trial, anxiety was lower during pregnancy and postnatally for RELAX plus UC participants compared with those receiving UC. Integrating RELAX into maternity care for those at risk of increased anxiety has potential to improve maternal mental health.

Corresponding Author: Colette R. Hirsch, PhD, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, De Crespigny Park, London, UK (colette.hirsch@kcl.ac.uk).

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