Original Investigation

Statin Initiation and Mortality After Colorectal Cancer Treatment

JAMA Network Open 10.1001/jamanetworkopen.2026.33680

September 15, 2026 at 11:00 AM EDT

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In this nationwide cohort study of adults treated for CRC, the survival benefit associated with statin initiation was modest and substantially attenuated compared with conventional observational estimates, suggesting that earlier protective associations may have reflected time-related biases and informative censoring.

Corresponding Author: Hyeong-taek Woo, MD, PhD, Department of Preventive Medicine, Keimyung University School of Medicine, 1095 Dalgubeol-daero, Dalseo-gu, Daegu 42601, Korea (since2002sz@gmail.com).

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