Cefepime and Mortality

This systematic review and bayesian meta-analysis found that cefepime was associated with higher odds of all-cause mortality compared with other β-lactams. These findings support a nuanced discussion of cefepime’s safety in guidance statements.

Corresponding Authors: Zahra N. Sohani, MD, PhD, Hôpital Maisonneuve-Rosemont, CIUSSS de l’Est-de-l’Île-de-Montréal, 5415 Boulevard de l’Assomption, Montreal, Quebec H1T 2M4, Canada (sohani.zahra@mayo.edu); Todd C. Lee, MD, MPH, McGill University Health Centre, 1001 Decarie Blvd, E5-1820, Montreal, Quebec H4A 3J1, Canada (todd.lee@mcgill.ca).

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